![]() ![]() However, PMMA bone cement is also a double-edged sword. Polymethyl methacrylate (PMMA) bone cement, as one of the materials used in vertebroplasty, can provide high strength support ( Zhang et al., 2018), reinforces the mechanical strength of the vertebral body ( Zhu et al., 2020), and has the advantages of low biological toxicity, easy operation ( Charnley, 1960), strong plasticity, high heat release during injection ( Lewis, 1997) for rapid analgesia of burned nerve tissue ( Yang, et al., 2020a) and restoration of vertebral body height ( Zhang et al., 2018). Percutaneous vertebroplasty was initially used to treat hemangioma, then to treat osteoporotic vertebral compression fractures, with remarkable results ( Zhang et al., 2018). With the development of medical technology, the human life span is also increasing, which will also lead to the population ageing aggravated and then cause the increasing incidence of osteoporosis and vertebral compression fractures ( Zhu et al., 2020), a serious problem threatening human health. ![]() Results: The stress distribution of the T11-L1 vertebral body was similar between the two bone types of cement under various stress conditions.Ĭonclusion: Mineralized collagen modified bone cement had the advantages of promoting bone regeneration, good biocompatibility, good transformability, and coupling, and had support strength not inferior to common PMMA bone cement, indicating it has good development prospects and potential. Methods: A healthy volunteer was selected to perform a three-dimensional reconstruction of the T11-L1 vertebral body to establish the corresponding finite element model of the spine, and the changes in the stress distribution of different types of cement were biomechanically analyzed in groups by applying quantitative loads. ![]() Objective: To investigate whether mineralized collagen modified polymethyl methacrylate (MC-PMMA) bone cement impacts the implanted vertebral body and adjacent segments and the feasibility of biomechanical properties compared with common bone cement in the treatment of osteoporotic vertebral compression fractures (OVCF).
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